Bleeding Disorders

Summary

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If
you have a bleeding disorder, you either do not have enough platelets or clotting factors
or they don’t work the way they should.

Bleeding disorders can be the result of other diseases, such as severe liver disease or a lack of vitamin K. They can also be inherited. Hemophilia is an inherited bleeding disorder. Bleeding disorders can also be a side effect of medicines such as blood thinners.

Various blood tests can check for a bleeding disorder. You will also have a physical exam and history. Treatments depend on the cause. They may include medicines and transfusions of blood, platelets, or clotting factor.

National Heart, Lung, and Blood Institute

Genetics

• Bernard-Soulier syndrome: MedlinePlus Genetics National Library of Medicine
• Complete plasminogen activator inhibitor 1 deficiency: MedlinePlus Genetics National Library of Medicine
• Factor V deficiency: MedlinePlus Genetics National Library of Medicine
• Factor VII deficiency: MedlinePlus Genetics National Library of Medicine
• Factor X deficiency: MedlinePlus Genetics National Library of Medicine
• Factor XI deficiency: MedlinePlus Genetics National Library of Medicine
• Factor XIII deficiency: MedlinePlus Genetics National Library of Medicine
• Glycoprotein VI deficiency: MedlinePlus Genetics National Library of Medicine
• Prekallikrein deficiency: MedlinePlus Genetics National Library of Medicine
• Prothrombin deficiency: MedlinePlus Genetics National Library of Medicine
• Stormorken syndrome: MedlinePlus Genetics National Library of Medicine
• Thrombocytopenia-absent radius syndrome: MedlinePlus Genetics National Library of Medicine
• Wiskott-Aldrich syndrome: MedlinePlus Genetics National Library of Medicine

Women

• Bleeding Disorders Department of Health and Human Services, Office on Women’s Health
• What Are Bleeding Disorders in Women? Centers for Disease Control and Prevention

Patient Handouts

• Bleeding disorders Medical Encyclopedia
• Bleeding time Medical Encyclopedia
• Disseminated intravascular coagulation (DIC) Medical Encyclopedia
• Partial thromboplastin time (PTT) Medical Encyclopedia
• Prothrombin time (PT) Medical Encyclopedia

Encyclopedia

• Bleeding into the skin Medical Encyclopedia
• Blood clotting Medical Encyclopedia
• Congenital fibrinogen deficiency Medical Encyclopedia
• Factor II assay Medical Encyclopedia
• Factor II deficiency Medical Encyclopedia
• Factor V assay Medical Encyclopedia
• Factor V deficiency Medical Encyclopedia
• Factor VII assay Medical Encyclopedia
• Factor VII deficiency Medical Encyclopedia
• Factor X assay Medical Encyclopedia
• Factor X deficiency Medical Encyclopedia
• Factor XII (Hageman factor) deficiency Medical Encyclopedia
• Factor XII assay Medical Encyclopedia
• Fibrin degradation products Medical Encyclopedia
• Fibrinogen Medical Encyclopedia
• Fibrinolysis – primary or secondary Medical Encyclopedia
• Fibrinopeptide A blood test Medical Encyclopedia
• Hemoglobinuria test Medical Encyclopedia
• Osler-Weber-Rendu syndrome Medical Encyclopedia
• Protein electrophoresis – serum Medical Encyclopedia
• Vitamin K deficiency bleeding of the newborn Medical Encyclopedia

Children

• Blood (For Parents) Nemours Foundation

Statistics and Research

• Blood Disorders Centers for Disease Control and Prevention

Treatments and Therapies

• Blood Thinners: MedlinePlus Health Topic National Library of Medicine

Teenagers

• Blood Transfusions (For Teens) Nemours Foundation

Start Here

• Bruising and Bleeding Merck & Co., Inc.
• What Are Blood Clotting Disorders? National Heart, Lung, and Blood Institute

Find an Expert

• Centers for Disease Control and Prevention Centers for Disease Control and Prevention
• Find a Hematologist American Society of Hematology
• National Heart, Lung, and Blood Institute National Heart, Lung, and Blood Institute
• Where to Donate Blood Association for the Advancement of Blood & Biotherapies

Clinical Trials

• ClinicalTrials.gov: Blood Coagulation Disorders National Institutes of Health

Diagnosis and Tests

• Coagulation Factor Tests National Library of Medicine
• D-Dimer Test National Library of Medicine
• MPV Blood Test National Library of Medicine
• Prothrombin Time Test and INR (PT/INR) National Library of Medicine

Specifics

• Disseminated Intravascular Coagulation (DIC) National Heart, Lung, and Blood Institute
• Rare Clotting Factor Deficiencies World Federation of Hemophilia
• What Is Vitamin K Deficiency Bleeding? Centers for Disease Control and Prevention

Journal Articles

• Bleeding disorders

Symptoms

• Signs and Symptoms of a Bleeding Disorder in Women Centers for Disease Control and Prevention

Living With

• Treatments for Blood Disorders National Heart, Lung, and Blood Institute