Sjogren’s Syndrome Summary Sjogren’s syndrome is a disease that causes dryness in your mouth and eyes. It can also lead to dryness in other places that need moisture, such as your nose, throat and skin. Most people who get Sjogren’s syndrome are older than 40. Nine of 10 are women. Sjogren’s syndrome is sometimes linked to rheumatic problems such as rheumatoid arthritis. Sjogren’s syndrome is an autoimmune disease. If you have an autoimmune disease, your immune system, which is supposed to fight disease, mistakenly attacks parts of your own body. In Sjogren’s syndrome, your immune system attacks the glands that make tears and saliva. It may also affect your joints, lungs, kidneys, blood vessels, digestive organs and nerves. The main symptoms are: Dry eyes Dry mouth Treatment focuses on relieving symptoms. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Arthritis and Musculoskeletal and Skin Diseases Diagnosis and Tests ANA (Antinuclear Antibody Test) American Association for Clinical Chemistry Antinuclear Antibodies (ANA) American College of Rheumatology Rheumatoid Factor American Association for Clinical Chemistry Encyclopedia Antithyroid microsomal antibody Salivary gland biopsy Schirmer test Clinical Trials ClinicalTrials.gov: Dry Eye Syndromes National Institutes of Health ClinicalTrials.gov: Sjogren’s Syndrome National Institutes of Health Specifics Dry Eye National Eye Institute Dry Skin Sjogren’s Syndrome Foundation MedlinePlus: Dry Mouth National Library of Medicine What Is Dry Eye? American Academy of Ophthalmology Start Here Dry Eyes and Mouth? You May Have Sjögren’s Syndrome National Institutes of Health Sjogren’s Syndrome Mayo Foundation for Medical Education and Research Sjogren’s Syndrome Information Page National Institute of Neurological Disorders and Stroke Sjögren’s Syndrome American College of Rheumatology Sjögren’s Syndrome National Institute of Arthritis and Musculoskeletal and Skin Diseases What Is Sjögren’s Syndrome? National Institute of Arthritis and Musculoskeletal and Skin Diseases Living With Fatigue Fighters in Sjogren’s Syndrome Sjogren’s Syndrome Foundation Sleep Tips for Sjogren’s Patients Sjogren’s Syndrome Foundation Tips for Chronic Pain Sjogren’s Syndrome Foundation Find an Expert Find a Rheumatologist American College of Rheumatology National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Dental and Craniofacial Research National Institute of Dental and Craniofacial Research National Institute of Neurological Disorders and Stroke National Institute of Neurological Disorders and Stroke Sjogren’s Syndrome Foundation Sjogren’s Syndrome Foundation Genetics Genetics Home Reference: Sjögren syndrome National Library of Medicine Statistics and Research New Genetic Susceptibility Factors for Sjögren’s Syndrome Revealed National Institute of Arthritis and Musculoskeletal and Skin Diseases Journal Articles Sjogren’s Syndrome Array Rheumatoid factor (RF) Sjogren syndrome Videos and Tutorials Sjogren’s Syndrome: A Place to Begin Sjogren’s Syndrome Foundation Related Issues Sjogren’s Syndrome: Can It Cause Recurrent UTIs? Mayo Foundation for Medical Education and Research Sun and Sjogren’s Syndrome Sjogren’s Syndrome Foundation Surgery, Hospitals, and Medications Sjogren’s Syndrome Foundation Tips for Airline Travelers with Sjogren’s Syndrome Sjogren’s Syndrome Foundation What Do I Need to Know about Sjogren’s Syndrome and Lupus? Lupus Foundation of America