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Lymphoma
Summary
Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas.
Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors don’t know why a person gets non-Hodgkin lymphoma. You are at increased risk if you have a weakened immune system or have certain types of infections.
Non-Hodgkin lymphoma can cause many symptoms, such as :
- Swollen, painless lymph nodes in the neck, armpits or groin
- Unexplained weight loss
- Fever
- Soaking night sweats
- Coughing, trouble breathing or chest pain
- Weakness and tiredness that don’t go away
- Pain, swelling or a feeling of fullness in the abdomen
Your doctor will diagnose lymphoma with a physical exam, blood tests, a chest x-ray, and a biopsy. Treatments include chemotherapy, radiation therapy, targeted therapy, biological therapy, or therapy to remove proteins from the blood. Targeted therapy uses drugs or other substances that attack specific cancer cells with less harm to normal cells. Biologic therapy boosts your body’s own ability to fight cancer. If you don’t have symptoms, you may not need treatment right away. This is called watchful waiting.
NIH: National Cancer Institute
National Cancer Institute
Encyclopedia
- 24-hour urine protein Medical Encyclopedia
- ACE blood test Medical Encyclopedia
- B and T cell screen Medical Encyclopedia
- Bone marrow transplant – discharge Medical Encyclopedia
- Bone-marrow transplant – series — Normal anatomy Medical Encyclopedia
- Chest radiation – discharge Medical Encyclopedia
- Cryoglobulins Medical Encyclopedia
- Cytology exam of pleural fluid Medical Encyclopedia
- Immunofixation – blood Medical Encyclopedia
- Immunofixation – urine Medical Encyclopedia
- Lymphangiogram Medical Encyclopedia
- Macroglobulinemia of Waldenstrom Medical Encyclopedia
- Mediastinal tumor Medical Encyclopedia
- Mediastinoscopy with biopsy Medical Encyclopedia
- Quantitative nephelometry test Medical Encyclopedia
- Serum globulin electrophoresis Medical Encyclopedia
- T-cell count Medical Encyclopedia
Genetics
- 8p11 myeloproliferative syndrome: MedlinePlus Genetics National Library of Medicine
- Mycosis fungoides: MedlinePlus Genetics National Library of Medicine
- Sézary syndrome: MedlinePlus Genetics National Library of Medicine
Specifics
- Adult T-Cell Leukemia/Lymphoma Lymphoma Research Foundation
- Anaplastic Large Cell Lymphoma Lymphoma Research Foundation
- Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Lymphoma Research Foundation
- General Information about AIDS-Related Lymphoma National Cancer Institute
- General Information about Mycosis Fungoides (Including Sézary Syndrome) National Cancer Institute
- General Information about Primary CNS Lymphoma National Cancer Institute
- Mantle Cell Lymphoma Lymphoma Research Foundation
- Marginal Zone Lymphoma Lymphoma Research Foundation
- T-Cell Lymphoma Lymphoma Research Foundation
- What Is Waldenstrom Macroglobulinema? American Cancer Society
Patient Handouts
- After chemotherapy – discharge Medical Encyclopedia
- B-cell leukemia/lymphoma panel Medical Encyclopedia
- Bone marrow transplant Medical Encyclopedia
- Burkitt lymphoma Medical Encyclopedia
- Lymph node biopsy Medical Encyclopedia
- Non-Hodgkin lymphoma Medical Encyclopedia
- Non-Hodgkin lymphoma – children Medical Encyclopedia
Find an Expert
- American Cancer Society American Cancer Society
- Find a Cancer Doctor American Society of Clinical Oncology
- Leukemia & Lymphoma Society Leukemia & Lymphoma Society
- Lymphoma Research Foundation Lymphoma Research Foundation
- National Cancer Institute National Cancer Institute
- NCI Designated Cancer Centers National Cancer Institute
Diagnosis and Tests
- Beta 2 Microglobulin (B2M) Tumor Marker Test National Library of Medicine
- Blood Count Tests: MedlinePlus Health Topic National Library of Medicine
- Bone Marrow Test National Library of Medicine
- Lab and Imaging Tests Leukemia & Lymphoma Society
- Needle Biopsy Mayo Foundation for Medical Education and Research
- Stages of Adult Non-Hodgkin Lymphoma National Cancer Institute
- Stages of AIDS-Related Lymphoma National Cancer Institute
- Stages of Childhood Non-Hodgkin Lymphoma National Cancer Institute
- Stages of Mycosis Fungoides (Including Sézary Syndrome) National Cancer Institute
- Staging Primary CNS Lymphoma National Cancer Institute
- Tests for Non-Hodgkin Lymphoma American Cancer Society
- Tests for Waldenstrom Macroglobulinemia American Cancer Society
- Tumor Marker Tests National Library of Medicine
Treatments and Therapies
- Blood-Forming Stem Cell Transplants National Cancer Institute
- Bone Marrow Transplantation: MedlinePlus Health Topic National Library of Medicine
- Drugs Approved for Non-Hodgkin Lymphoma National Cancer Institute
- Immunotherapy Leukemia & Lymphoma Society
- Integrative Medicine and Complementary and Alternative Therapies Leukemia & Lymphoma Society
- Radioimmunotherapy (RIT) Radiological Society of North America
- Treatment of Recurrent Mycosis Fungoides (Including Sézary Syndrome) National Cancer Institute
- Treatment of Stage I and Stage II Mycosis Fungoides National Cancer Institute
- Treatment of Stage III and Stage IV Mycosis Fungoides (Including Sézary Syndrome) National Cancer Institute
- Treatment Option Overview (Adult Non-Hodgkin Lymphoma) National Cancer Institute
- Treatment Option Overview (AIDS Related-Lymphoma) National Cancer Institute
- Treatment Option Overview (Childhood Non-Hodgkin Lymphoma) National Cancer Institute
- Treatment Option Overview (Primary CNS Lymphoma) National Cancer Institute
- Treatment Option Overview for Mycosis Fungoides (Including Sézary Syndrome) National Cancer Institute
- Treatment Options for Childhood Non-Hodgkin Lymphoma National Cancer Institute
Prevention and Risk Factors
- Can Non-Hodgkin Lymphoma Be Prevented? American Cancer Society
- Non-Hodgkin Lymphoma Risk Factors American Cancer Society
- What Are the Risk Factors for Waldenstrom Macroglobulinemia? American Cancer Society
Statistics and Research
- Cancer Stat Facts: Non-Hodgkin Lymphoma National Cancer Institute
- Key Statistics for Non-Hodgkin Lymphoma American Cancer Society
- What’s New in Non-Hodgkin Lymphoma Research and Treatment? American Cancer Society
Clinical Trials
- ClinicalTrials.gov: Lymphoma National Institutes of Health
- ClinicalTrials.gov: Lymphoma, Non-Hodgkin National Institutes of Health
- ClinicalTrials.gov: Waldenstrom Macroglobulinemia National Institutes of Health
- Types of Treatment: Clinical Trials Leukemia & Lymphoma Society
Start Here
- General Information about Adult Non-Hodgkin Lymphoma National Cancer Institute
- General Information about Childhood Non-Hodgkin Lymphoma National Cancer Institute
- Non-Hodgkin’s Lymphoma Mayo Foundation for Medical Education and Research
- What Is Non-Hodgkin Lymphoma? American Cancer Society
Living With
- Getting the Facts: Cancer-Related Fatigue Lymphoma Research Foundation
- Living as a Non-Hodgkin Lymphoma Survivor American Cancer Society
- Living as a Waldenstrom Macroglobulinemia Survivor American Cancer Society
Children
- Immunotherapy (For Parents) Nemours Foundation
- What Causes Non-Hodgkin Lymphoma in Children? American Cancer Society
Journal Articles
Related Issues
- What’s the Difference between Hodgkin’s Lymphoma and Non-Hodgkin’s Lymphoma? Mayo Foundation for Medical Education and Research