Endometriosis

Summary

What is endometriosis?

The uterus, or womb, is the place where a baby grows when a person is pregnant. The uterus is lined with tissue (endometrium). Endometriosis is a disease in which tissue that is similar to the lining of the uterus grows in other places in your body. These patches of tissue are called “implants,” “nodules,” or “lesions.” They are most often found:

• On or under the ovaries
• On the fallopian tubes, which carry egg cells from the ovaries to the uterus
• Behind the uterus
• On the tissues that hold the uterus in place
• On the bowels or bladder

In rare cases, the tissue may grow on your lungs or in other parts of your body.

What causes endometriosis?

The cause of endometriosis is unknown.

Who is at risk for endometriosis?

Endometriosis can affect anyone who menstruates. Certain factors can raise or lower your risk of getting it.

You are at higher risk if:

• You have a mother, sister, or daughter with endometriosis
• Your period started before age 11
• Your monthly cycles are short (less than 27 days)
• Your menstrual cycles are heavy and last more than 7 days

You have a lower risk if:

• You have been pregnant before
• Your periods started late in adolescence
• You breastfeed your babies

What are the symptoms of endometriosis?

The main symptoms of endometriosis are:

• Pelvic pain, which often happens during your period.
• Infertility

Other possible symptoms include:

• Painful menstrual cramps, which may get worse over time
• Pain during or after sex
• Pain in the intestine or lower abdomen
• Pain with bowel movements or urination, usually during your period
• Heavy periods
• Spotting or bleeding between periods
• Digestive or gastrointestinal symptoms
• Fatigue or lack of energy

How is endometriosis diagnosed?

Surgery is the only way to know for sure that you have endometriosis. First, however, your health care provider will ask about your symptoms and medical history. You will have a pelvic exam and may have some imaging tests.

The most common surgery to diagnose endometriosis is a laparoscopy. This is a type of surgery that uses a laparoscope, a thin tube with a camera and light. The surgeon inserts the laparoscope through a small cut in the skin. Your provider can make a diagnosis based on how the patches of endometriosis look. He or she may also do a biopsy to get a tissue sample.

What are the treatments for endometriosis?

There is no cure for endometriosis, but there are treatments for the symptoms. Your provider will work with you to decide which treatments would be best for you.

Treatments for endometriosis pain include:

• Pain relievers, including nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen and a prescription medicine specifically for endometriosis. Providers may sometimes prescribe opioids for severe pain.
• Hormone therapy, including birth control pills, progestin therapy, and gonadotropin-releasing hormone (GnRH) agonists. GnRH agonists cause a temporary menopause, but also help control the growth of endometriosis.
• Surgical treatments for severe pain, including procedures to remove the endometriosis patches or cut some nerves in the pelvis. The surgery may be a laparoscopy or major surgery.

Treatments for infertility caused by endometriosis include:

• Laparoscopy to remove the endometriosis patches
• In vitro fertilization

NIH: National Institute of Child Health and Human Development

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Encyclopedia

• Abdominal exploration Medical Encyclopedia
• Diagnostic laparoscopy Medical Encyclopedia
• Pelvic laparoscopy Medical Encyclopedia
• Pelvis MRI scan Medical Encyclopedia

Diagnosis and Tests

• Abdominal exploration – series — Normal anatomy Medical Encyclopedia
• How Do Health Care Providers Diagnose Endometriosis? Eunice Kennedy Shriver National Institute of Child Health and Human Development
• Laparoscopy National Library of Medicine
• Pneumothorax – series — Normal Medical Encyclopedia

Specifics

• Adenomyosis Mayo Foundation for Medical Education and Research

Clinical Trials

• ClinicalTrials.gov: Adenomyosis National Institutes of Health
• ClinicalTrials.gov: Endometriosis National Institutes of Health

Find an Expert

• Department of Health and Human Services, Office on Women’s Health Department of Health and Human Services, Office on Women’s Health
• Eunice Kennedy Shriver National Institute of Child Health and Human Development Eunice Kennedy Shriver National Institute of Child Health and Human Development
• Find an Ob-Gyn American College of Obstetricians and Gynecologists

Videos and Tutorials

• Endometriosis American Society for Reproductive Medicine

Start Here

• Endometriosis Mayo Foundation for Medical Education and Research
• Endometriosis Department of Health and Human Services, Office on Women’s Health
• What Is Endometriosis? Eunice Kennedy Shriver National Institute of Child Health and Human Development

Patient Handouts

• Endometriosis Medical Encyclopedia
• Living with endometriosis Medical Encyclopedia

Teenagers

• Endometriosis (For Teens) Nemours Foundation
• Endometriosis: General Information Boston Children’s Hospital

Treatments and Therapies

• Endometriosis and Infertility: Can Surgery Help? American Society for Reproductive Medicine
• What Are the Treatments for Endometriosis? Eunice Kennedy Shriver National Institute of Child Health and Human Development

Related Issues

• Endometriosis: Does It Cause Infertility? American Society for Reproductive Medicine
• Period Problems: Fibroids, Endometriosis, and Other Issues National Institutes of Health

Reference Desk

• Female Reproductive System National Cancer Institute

NIH MedlinePlus Magazine

• Improving Endometriosis Diagnosis Through Research and Awareness
• Inheriting Endometriosis

Journal Articles

• Endometriosis

Prevention and Risk Factors

• What Are the Risk Factors for Endometriosis? Eunice Kennedy Shriver National Institute of Child Health and Human Development

Symptoms

• What Are the Symptoms of Endometriosis? Eunice Kennedy Shriver National Institute of Child Health and Human Development