Ehlers-Danlos Syndrome Also called: Cutis elastica, EDS Summary Ehlers-Danlos syndrome (EDS) is a group of inherited disorders that weaken connective tissues. Connective tissues are proteins that support skin, bones, blood vessels, and other organs. EDS usually affects your skin, joints and blood vessel walls. Symptoms include Loose joints Fragile, small blood vessels Abnormal scar formation and wound healing Soft, velvety, stretchy skin that bruises easily There are several types of EDS. They can range from mild to life-threatening. About 1 in 5,000 people has EDS. There is no cure. Treatment involves managing symptoms, often with medicines and physical therapy. It also includes learning how to protect your joints and prevent injuries. National Institute of Arthritis and Musculoskeletal and Skin Diseases Clinical Trials ClinicalTrials.gov: Ehlers-Danlos Syndrome National Institutes of Health Resources Ehlers-Danlos Syndrome Mayo Foundation for Medical Education and Research Ehlers-Danlos syndrome Ehlers-Danlos Syndrome Hypermobility Type Marfan Foundation Ehlers-Danlos Syndrome: Causes and Symptoms Ehlers-Danlos Syndrome Network C.A.R.E.S. Ehlers-Danlos Syndrome: Myths and Facts Ehlers-Danlos Syndrome Network C.A.R.E.S. Genetics Home Reference: Ehlers-Danlos syndrome National Library of Medicine Heritable Disorders of Connective Tissue National Institute of Arthritis and Musculoskeletal and Skin Diseases Journal Articles Ehlers-Danlos Syndrome