Pemphigus

Summary

Pemphigus is an autoimmune disorder. If you have it, your immune system attacks healthy cells in your skin and mouth, causing blisters and sores. No one knows the cause. Pemphigus does not spread from person to person. It does not appear to be inherited. But some people’s genes put them more at risk for pemphigus.

Pemphigoid is also an autoimmune skin disease. It leads to deep blisters that do not break easily. Pemphigoid is most common in older adults and may be fatal for older, sick patients.

Doctors diagnose pemphigus with a physical exam, a biopsy, and blood tests. The treatment of pemphigus and pemphigoid is the same: one or more medicines to control symptoms. These may include:

• Steroids, which reduce inflammation
• Drugs that suppress the immune system response
• Antibiotics to treat associated infections

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Specifics

• Bullous Pemphigoid American Osteopathic College of Dermatology
• Cicatricial Pemphigoid American Academy of Oral and Maxillofacial Pathology
• Hailey-Hailey Disease (Benign Chronic Pemphigus) American Osteopathic College of Dermatology

Patient Handouts

• Bullous pemphigoid Medical Encyclopedia
• Pemphigus vulgaris Medical Encyclopedia

Clinical Trials

• ClinicalTrials.gov: Pemphigoid, Benign Mucous Membrane National Institutes of Health
• ClinicalTrials.gov: Pemphigoid, Bullous National Institutes of Health
• ClinicalTrials.gov: Pemphigus National Institutes of Health

Find an Expert

• Find a Dermatologist American Academy of Dermatology
• National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Arthritis and Musculoskeletal and Skin Diseases

Encyclopedia

• Nikolsky sign Medical Encyclopedia

Start Here

• Pemphigus National Institute of Arthritis and Musculoskeletal and Skin Diseases

Images

• Pemphigus Vulgaris VisualDX

Journal Articles

• Pemphigus