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Blood Clots
Summary
What is a blood clot?
A blood clot is mass of blood that forms when platelets, proteins, and cells in the blood stick together. When you get hurt, your body forms a blood clot to stop the bleeding. After the bleeding stops and healing takes place, your body usually breaks down and removes the blood clot. But sometimes the blood clots form where they shouldn’t, your body makes too many blood clots or abnormal blood clots, or the blood clots don’t break down like they should. These blood clots can be dangerous and may cause other health problems.
Blood clots can form in, or travel to, the blood vessels in the limbs, lungs, brain, heart, and kidneys. The types of problems blood clots can cause will depend on where they are:
- Deep vein thrombosis (DVT) is a blood clot in a deep vein, usually in the lower leg, thigh, or pelvis. It can block a vein and cause damage to your leg.
- A pulmonary embolism can happen when a DVT breaks off and travels through the bloodstream to the lungs. It can damage your lungs and prevent your other organs from getting enough oxygen.
- Cerebral venous sinus thrombosis (CVST) is a rare blood clot in the venous sinuses in your brain. Normally the venous sinuses drain blood from your brain. CVST blocks the blood from draining and can cause a hemorrhagic stroke.
- Blood clots in other parts of the body can cause problems such as an ischemic stroke, a heart attack, kidney problems, kidney failure, and pregnancy-related problems.
Who is at risk for blood clots?
Certain factors can raise the risk of blood clots:
- Atherosclerosis
- Atrial fibrillation
- Cancer and cancer treatments
- Certain genetic disorders
- Certain surgeries
- COVID-19
- Diabetes
- Family history of blood clots
- Overweight and obesity
- Pregnancy and giving birth
- Serious injuries
- Some medicines, including birth control pills
- Smoking
- Staying in one position for a long time, such as being in the hospital or taking a long car or plane ride
What are the symptoms of blood clots?
The symptoms for blood clots can be different, depending on where the blood clot is:
- In the abdomen: Abdominal pain, nausea and vomiting
- In an arm or leg: Sudden or gradual pain, swelling, tenderness, and warmth
- In the lungs: Shortness of breath, pain with deep breathing, rapid breathing, and increased heart rate
- In the brain: Trouble speaking, vision problems, seizures, weakness on one side of the body, and sudden severe headache
- In the heart: Chest pain, sweating, shortness of breath, and pain in the left arm
How are blood clots diagnosed?
Your health care provider may use many tools to diagnose blood clots:
- A physical exam
- A medical history
- Blood tests, including a D-dimer test
- Imaging tests, such as
- Ultrasound
- X-rays of the veins (venography) or blood vessels (angiography) that are taken after you get an injection of special dye. The dye shows up on the x-ray and allows the provider to see how the blood flows.
- CT Scan
What are the treatments for blood clots?
Treatments for blood clots depend on where the blood clot is located and how severe it is. Treatments may include:
- Blood thinners
- Other medicines, including thrombolytics. Thrombolytics are medicines which dissolve blood clots. They are usually used where the blood clots are severe.
- Surgery and other procedures to remove the blood clots
Can blood clots be prevented?
You may be able to help prevent blood clots by:
- Moving around as soon as possible after having been confined to your bed, such as after surgery, illness, or injury
- Getting up and moving around every few hours when you have to sit for long periods of time, for example if you are on a long flight or car trip
- Regular physical activity
- Not smoking
- Staying at a healthy weight
Some people at high risk may need to take blood thinners to prevent blood clots.
National Heart, Lung, and Blood Institute
Specifics
- Antiphospholipid Syndrome National Institute of Neurological Disorders and Stroke
- Antiphospholipid Syndrome (APS) National Heart, Lung, and Blood Institute
- Cerebral and Sinus Vein Thrombosis American Heart Association
- Cerebral Venous Sinus Thrombosis (CVST) Johns Hopkins Medicine
- Disseminated Intravascular Coagulation (DIC) National Heart, Lung, and Blood Institute
- Hypercoagulation American Academy of Family Physicians
- Thrombophlebitis Mayo Foundation for Medical Education and Research
- Thrombotic Thrombocytopenic Purpura (TTP) National Heart, Lung, and Blood Institute
Encyclopedia
- Antithrombin III blood test Medical Encyclopedia
- Blood clotting Medical Encyclopedia
- Cavernous sinus thrombosis Medical Encyclopedia
- Congenital antithrombin III deficiency Medical Encyclopedia
- Congenital protein C or S deficiency Medical Encyclopedia
- Disseminated intravascular coagulation (DIC) Medical Encyclopedia
- Fibrin degradation products Medical Encyclopedia
- Fibrinogen Medical Encyclopedia
- Fibrinopeptide A blood test Medical Encyclopedia
- Lupus anticoagulants and antiphospholipid antibodies Medical Encyclopedia
- Partial thromboplastin time (PTT) Medical Encyclopedia
- Protein C blood test Medical Encyclopedia
- Protein S blood test Medical Encyclopedia
- Renal vein thrombosis Medical Encyclopedia
Patient Handouts
- Arterial embolism Medical Encyclopedia
- Blood clots Medical Encyclopedia
- D-dimer test Medical Encyclopedia
- Prothrombin time (PT) Medical Encyclopedia
- Superficial thrombophlebitis Medical Encyclopedia
- Thrombophlebitis Medical Encyclopedia
Children
- Blood (For Parents) Nemours Foundation
Start Here
- Blood Clots Radiological Society of North America
- Blood Clots American Society of Hematology
- Blood Clots Mayo Foundation for Medical Education and Research
- How Blood Clots Merck & Co., Inc.
Related Issues
- Blood Clots and Travel: What You Need to Know Centers for Disease Control and Prevention
- Blood Thinners: Can I Still Get Blood Clots? Mayo Foundation for Medical Education and Research
- Selected Adverse Events Reported after COVID-19 Vaccination Centers for Disease Control and Prevention
- Understand Your Risk for Excessive Blood Clotting American Heart Association
Statistics and Research
- Blood Clots Explained: Clearing Blockages in the System National Institutes of Health
Treatments and Therapies
- Blood Thinners: MedlinePlus Health Topic National Library of Medicine
- Catheter-Directed Thrombolysis Radiological Society of North America
Find an Expert
- Centers for Disease Control and Prevention Centers for Disease Control and Prevention
- Find a Hematologist American Society of Hematology
- National Heart, Lung, and Blood Institute National Heart, Lung, and Blood Institute
Clinical Trials
- ClinicalTrials.gov: Thrombophlebitis National Institutes of Health
- ClinicalTrials.gov: Thrombosis National Institutes of Health
- ClinicalTrials.gov: Venous Thrombosis National Institutes of Health
Diagnosis and Tests
- Coagulation Factor Tests National Library of Medicine
- D-Dimer Test National Library of Medicine
- MPV Blood Test National Library of Medicine
- Partial Thromboplastin Time (PTT) Test National Library of Medicine
- Protein C and Protein S Tests National Library of Medicine
- Prothrombin Time Test and INR (PT/INR) National Library of Medicine
Genetics
- Factor V Leiden thrombophilia: MedlinePlus Genetics National Library of Medicine
- Hereditary antithrombin deficiency: MedlinePlus Genetics National Library of Medicine
- Learning about Antiphospholipid Syndrome (APS) National Human Genome Research Institute
- Learning about Factor V Leiden Thrombophilia National Human Genome Research Institute
- Protein C deficiency: MedlinePlus Genetics National Library of Medicine
- Protein S deficiency: MedlinePlus Genetics National Library of Medicine
- Prothrombin thrombophilia: MedlinePlus Genetics National Library of Medicine
Women
- Postpartum Blood Clots Merck & Co., Inc.