Clostridium Difficile Infections Also called: C. diff. infections, Clostridium enterocolitis, pseudomembranous colitis Summary Clostridium difficile (C. difficile) is a bacterium that causes diarrhea and more serious intestinal conditions such as colitis. Symptoms include Watery diarrhea (at least three bowel movements per day for two or more days) Fever Loss of appetite Nausea Abdominal pain or tenderness You might get C. difficile disease if you have an illness that requires prolonged use of antibiotics. Increasingly, the disease can also be spread in the hospital. The elderly are also at risk. Treatment is with antibiotics. Centers for Disease Control and Prevention Specifics Antibiotic-Associated Diarrhea Mayo Foundation for Medical Education and Research Information about the Current Strain of Clostridium difficile Centers for Disease Control and Prevention Pseudomembranous colitis Mayo Foundation for Medical Education and Research Related Issues Antibiotic-Associated Diarrhea Caused by Clostridium difficile (Beyond the Basics) UpToDate Treatments and Therapies C. difficile Infection American College of Gastroenterology Oral Probiotics National Center for Complementary and Integrative Health Start Here C. difficile Infection Mayo Foundation for Medical Education and Research Clostridium difficile Infection American Academy of Family Physicians Find an Expert Centers for Disease Control and Prevention Centers for Disease Control and Prevention National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases Clinical Trials ClinicalTrials.gov: Clostridium difficile Infections National Institutes of Health ClinicalTrials.gov: Enterocolitis, Pseudomembranous National Institutes of Health Children Clostridium difficile American Academy of Pediatrics Stool Test: C. Difficile Toxin (For Parents) Nemours Foundation Diagnosis and Tests Clostridium difficile and C. difficile Toxin Testing American Association for Clinical Chemistry Array FAQs about Clostridium Difficile Centers for Disease Control and Prevention Pseudomembranous colitis Stool C. difficile toxin Journal Articles Clostridium Difficile Infections Seniors Special Concerns for Seniors: Clostridium difficile Alliance for the Prudent Use of Antibiotics