Degenerative Nerve Diseases Summary Degenerative nerve diseases affect many of your body’s activities, such as balance, movement, talking, breathing, and heart function. Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is not known. Degenerative nerve diseases include Alzheimer’s disease Amyotrophic lateral sclerosis Friedreich’s ataxia Huntington’s disease Lewy body disease Parkinson’s disease Spinal muscular atrophy Degenerative nerve diseases can be serious or life-threatening. It depends on the type. Most of them have no cure. Treatments may help improve symptoms, relieve pain, and increase mobility. National Institute of Neurological Disorders and Stroke Specifics Alpers’ Disease National Institute of Neurological Disorders and Stroke Batten Disease National Institute of Neurological Disorders and Stroke Batten Disease National Institute of Neurological Disorders and Stroke Cerebro-Oculo-Facio-Skeletal Syndrome (COFS) National Institute of Neurological Disorders and Stroke Corticobasal Degeneration National Institute of Neurological Disorders and Stroke Gerstmann-Straussler-Scheinker Disease National Institute of Neurological Disorders and Stroke Kuru National Institute of Neurological Disorders and Stroke Leigh’s Disease National Institute of Neurological Disorders and Stroke Monomelic Amyotrophy National Institute of Neurological Disorders and Stroke Multiple System Atrophy National Institute of Neurological Disorders and Stroke Multiple System Atrophy National Institute of Neurological Disorders and Stroke Multiple System Atrophy with Orthostatic Hypotension (Shy-Drager Syndrome) National Institute of Neurological Disorders and Stroke Neurodegeneration with Brain Iron Accumulation National Institute of Neurological Disorders and Stroke Opsoclonus Myoclonus National Institute of Neurological Disorders and Stroke Prion Diseases National Institute of Allergy and Infectious Diseases Progressive Multifocal Leukoencephalopathy National Institute of Neurological Disorders and Stroke Striatonigral Degeneration National Institute of Neurological Disorders and Stroke Transmissible Spongiform Encephalopathies (Prion Diseases) National Institute of Neurological Disorders and Stroke What Is Batten Disease Batten Disease Support and Research Association Clinical Trials ClinicalTrials.gov: Ataxia National Institutes of Health ClinicalTrials.gov: Neurodegenerative Diseases National Institutes of Health ClinicalTrials.gov: Prion Diseases National Institutes of Health Diagnosis and Tests Electromyography (EMG) Mayo Foundation for Medical Education and Research Specialized Nerve Tests: EMG, NCV and SSEP North American Spine Society Children EMG (Electromyography) (For Parents) Nemours Foundation Find an Expert Find a Neurologist American Academy of Neurology Find a Physical Medicine & Rehabilitation Physician American Academy of Physical Medicine and Rehabilitation National Institute of Neurological Disorders and Stroke National Institute of Neurological Disorders and Stroke Genetics Genetics Home Reference: Alexander disease National Library of Medicine Genetics Home Reference: Alpers-Huttenlocher syndrome National Library of Medicine Genetics Home Reference: alpha-methylacyl-CoA racemase deficiency National Library of Medicine Genetics Home Reference: Andermann syndrome National Library of Medicine Genetics Home Reference: Arts syndrome National Library of Medicine Genetics Home Reference: ataxia neuropathy spectrum National Library of Medicine Genetics Home Reference: ataxia with oculomotor apraxia National Library of Medicine Genetics Home Reference: autosomal recessive spastic ataxia of Charlevoix-Saguenay National Library of Medicine Genetics Home Reference: congenital insensitivity to pain with anhidrosis National Library of Medicine Genetics Home Reference: congenital neuronal ceroid lipofuscinosis National Library of Medicine Genetics Home Reference: familial encephalopathy with neuroserpin inclusion bodies National Library of Medicine Genetics Home Reference: fatty acid hydroxylase-associated neurodegeneration National Library of Medicine Genetics Home Reference: GM2-gangliosidosis, AB variant National Library of Medicine Genetics Home Reference: hereditary sensory and autonomic neuropathy type IE National Library of Medicine Genetics Home Reference: hereditary sensory and autonomic neuropathy type II National Library of Medicine Genetics Home Reference: hereditary sensory and autonomic neuropathy type V National Library of Medicine Genetics Home Reference: infantile neuroaxonal dystrophy National Library of Medicine Genetics Home Reference: infantile neuronal ceroid lipofuscinosis National Library of Medicine Genetics Home Reference: infantile-onset ascending hereditary spastic paralysis National Library of Medicine Genetics Home Reference: infantile-onset spinocerebellar ataxia National Library of Medicine Genetics Home Reference: juvenile Batten disease National Library of Medicine Genetics Home Reference: juvenile primary lateral sclerosis National Library of Medicine Genetics Home Reference: Kufs disease National Library of Medicine Genetics Home Reference: late-infantile neuronal ceroid lipofuscinosis National Library of Medicine Genetics Home Reference: Marinesco-Sjögren syndrome National Library of Medicine Genetics Home Reference: mitochondrial membrane protein-associated neurodegeneration National Library of Medicine Genetics Home Reference: multiple system atrophy National Library of Medicine Genetics Home Reference: neuromyelitis optica National Library of Medicine Genetics Home Reference: pantothenate kinase-associated neurodegeneration National Library of Medicine Genetics Home Reference: polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy National Library of Medicine Genetics Home Reference: prion disease National Library of Medicine Genetics Home Reference: progressive external ophthalmoplegia National Library of Medicine Genetics Home Reference: riboflavin transporter deficiency neuronopathy National Library of Medicine Genetics Home Reference: Sandhoff disease National Library of Medicine Encyclopedia Kuru Neuronal ceroid lipofuscinoses (NCLS) Riley-Day syndrome Secondary parkinsonism Start Here Motor Neuron Diseases National Institute of Neurological Disorders and Stroke Motor Neuron Diseases National Institute of Neurological Disorders and Stroke Array Multiple system atrophy Nerve conduction Progressive multifocal leukoencephalopathy Journal Articles Degenerative Nerve Diseases