Anaphylaxis Summary Anaphylaxis is a serious allergic reaction. It can begin very quickly, and symptoms may be life-threatening. The most common causes are reactions to foods (especially peanuts), medications, and stinging insects. Other causes include exercise and exposure to latex. Sometimes no cause can be found. It can affect many organs: Skin – itching, hives, redness, swelling Nose – sneezing, stuffy nose, runny nose Mouth – itching, swelling of the lips or tongue Throat – itching, tightness, trouble swallowing, swelling of the back of the throat Chest – shortness of breath, coughing, wheezing, chest pain or tightness Heart – weak pulse, passing out, shock Gastrointestinal tract – vomiting, diarrhea, cramps Nervous system – dizziness or fainting If someone is having a serious allergic reaction, call 9-1-1. If an auto-injector is available, give the person the injection right away. NIH: National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases Resources Anaphylaxis National Institute of Allergy and Infectious Diseases Anaphylaxis American Academy of Allergy, Asthma, and Immunology Anaphylaxis Anaphylaxis (Severe Allergic Reaction): First Aid Mayo Foundation for Medical Education and Research Anaphylaxis Quiz American Academy of Allergy, Asthma, and Immunology Anaphylaxis-Like Reactions National Jewish Health Serious Allergic Reactions (Anaphylaxis) Nemours Foundation Clinical Trials ClinicalTrials.gov: Anaphylaxis National Institutes of Health Journal Articles Anaphylaxis