Amyloidosis Summary Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should. There are three main types of amyloidosis: Primary – with no known cause Secondary – caused by another disease, including some types of cancer Familial – passed down through genes Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated. Encyclopedia Abdominal wall fat pad biopsy Carpal tunnel biopsy Cerebral amyloid angiopathy Related Issues AL Amyloidosis and Agent Orange Department of Veterans Affairs General Information about Plasma Cell Neoplasms (Including Multiple Myeloma) National Cancer Institute Start Here Amyloidosis Mayo Foundation for Medical Education and Research Amyloidosis American Society of Clinical Oncology Amyloidosis and Kidney Disease National Institute of Diabetes and Digestive and Kidney Diseases Find an Expert Amyloidosis Foundation Amyloidosis Foundation National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Diabetes and Digestive and Kidney Diseases Diagnosis and Tests Bone Marrow Aspiration and Biopsy American Association for Clinical Chemistry Serum Free Light Chains American Association for Clinical Chemistry Urine Protein and Urine Protein to Creatinine Ratio American Association for Clinical Chemistry Specifics Cardiac Amyloidosis American Heart Association Array Cardiac amyloidosis Hereditary amyloidosis Primary amyloidosis Secondary systemic amyloidosis Clinical Trials ClinicalTrials.gov: Amyloidosis National Institutes of Health Genetics Genetics Home Reference: hereditary cerebral amyloid angiopathy National Library of Medicine Genetics Home Reference: lattice corneal dystrophy type II National Library of Medicine Genetics Home Reference: transthyretin amyloidosis National Library of Medicine Genetics Home Reference: tumor necrosis factor receptor-associated periodic syndrome National Library of Medicine Journal Articles Amyloidosis